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An Increase in Reactive Oxygen Species by Deregulation of ARNT Enhances Chemotherapeutic Drug-Induced Cancer Cell Death

BACKGROUND: Unique characteristics of tumor microenvironments can be used as targets of cancer therapy. The aryl hydrocarbon receptor nuclear translocator (ARNT) is an important mediator of tumor progression. However, the functional role of ARNT in chemotherapeutic drug-treated cancer remains unclea...

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Detalles Bibliográficos
Autores principales: Shieh, Jiunn-Min, Shen, Chih-Jie, Chang, Wei-Chiao, Cheng, Hung-Chi, Chan, Ya-Yi, Huang, Wan-Chen, Chang, Wen-Chang, Chen, Ben-Kuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055634/
https://www.ncbi.nlm.nih.gov/pubmed/24921657
http://dx.doi.org/10.1371/journal.pone.0099242