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Protective Immunity Based on the Conserved Hemagglutinin Stalk Domain and Its Prospects for Universal Influenza Vaccine Development

Influenza virus surface glycoprotein hemagglutinin (HA) is an excellent and chief target that elicits neutralizing antibodies during vaccination or natural infection. Its HA2 subunit (stem domain) is most conserved as compared to HA1 subunit (globular head domain). Current influenza vaccine relies o...

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Detalles Bibliográficos
Autores principales: Khanna, Madhu, Sharma, Sachin, Kumar, Binod, Rajput, Roopali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055638/
https://www.ncbi.nlm.nih.gov/pubmed/24982895
http://dx.doi.org/10.1155/2014/546274