Comparative Response of Platelet fV and Plasma fV to Activated Protein C and Relevance to a Model of Acute Traumatic Coagulopathy

BACKGROUND: Acute traumatic coagulopathy (ATC) has been linked to an increase in activated protein C (aPC) from 40 pM in healthy individuals to 175 pM. aPC exerts its activity primarily through cleavage of active coagulation factor Va (fVa). Platelets reportedly possess fVa which is more resistant t...

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Detalles Bibliográficos
Autores principales: Campbell, James E., Meledeo, Michael Adam, Cap, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055642/
https://www.ncbi.nlm.nih.gov/pubmed/24921658
http://dx.doi.org/10.1371/journal.pone.0099181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055642/
https://www.ncbi.nlm.nih.gov/pubmed/24921658
http://dx.doi.org/10.1371/journal.pone.0099181

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