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Comparability of a Three-Dimensional Structure in Biopharmaceuticals Using Spectroscopic Methods
Protein structure depends on weak interactions and covalent bonds, like disulfide bridges, established according to the environmental conditions. Here, we present the validation of two spectroscopic methodologies for the measurement of free and unoxidized thiols, as an attribute of structural integr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055658/ https://www.ncbi.nlm.nih.gov/pubmed/24963443 http://dx.doi.org/10.1155/2014/950598 |