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Comparability of a Three-Dimensional Structure in Biopharmaceuticals Using Spectroscopic Methods

Protein structure depends on weak interactions and covalent bonds, like disulfide bridges, established according to the environmental conditions. Here, we present the validation of two spectroscopic methodologies for the measurement of free and unoxidized thiols, as an attribute of structural integr...

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Detalles Bibliográficos
Autores principales: Pérez Medina Martínez, Víctor, Abad-Javier, Mario E., Romero-Díaz, Alexis J., Villaseñor-Ortega, Francisco, Pérez, Néstor O., Flores-Ortiz, Luis F., Medina-Rivero, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055658/
https://www.ncbi.nlm.nih.gov/pubmed/24963443
http://dx.doi.org/10.1155/2014/950598