Tumor-Derived Interleukin-1 Promotes Lymphangiogenesis and Lymph Node Metastasis through M2-Type Macrophages

Tumors formed by a highly metastatic human lung cancer cell line are characterized by activated signaling via vascular endothelial growth factor (VEGF)-C through its receptor (VEGFR-3) and aggressive lymph node metastasis. In this study, we examined how these highly metastatic cancers acquired aggre...

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Detalles Bibliográficos
Autores principales: Watari, Kosuke, Shibata, Tomohiro, Kawahara, Akihiko, Sata, Ken-ichi, Nabeshima, Hiroshi, Shinoda, Ai, Abe, Hideyuki, Azuma, Koichi, Murakami, Yuichi, Izumi, Hiroto, Takahashi, Takashi, Kage, Masayoshi, Kuwano, Michihiko, Ono, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055709/
https://www.ncbi.nlm.nih.gov/pubmed/24924428
http://dx.doi.org/10.1371/journal.pone.0099568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055709/
https://www.ncbi.nlm.nih.gov/pubmed/24924428
http://dx.doi.org/10.1371/journal.pone.0099568

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