The Glycosylated Rv1860 Protein of Mycobacterium tuberculosis Inhibits Dendritic Cell Mediated TH1 and TH17 Polarization of T Cells and Abrogates Protective Immunity Conferred by BCG

We previously reported interferon gamma secretion by human CD4(+) and CD8(+) T cells in response to recombinant E. coli-expressed Rv1860 protein of Mycobacterium tuberculosis (MTB) as well as protection of guinea pigs against a challenge with virulent MTB following prime-boost immunization with DNA...

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Detalles Bibliográficos
Autores principales: Satchidanandam, Vijaya, Kumar, Naveen, Jumani, Rajiv S., Challu, Vijay, Elangovan, Shobha, Khan, Naseem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055742/
https://www.ncbi.nlm.nih.gov/pubmed/24945624
http://dx.doi.org/10.1371/journal.ppat.1004176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055742/
https://www.ncbi.nlm.nih.gov/pubmed/24945624
http://dx.doi.org/10.1371/journal.ppat.1004176

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