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New Environment-Sensitive Multichannel DNA Fluorescent Label for Investigation of the Protein-DNA Interactions

Here, we report the study of a new multichannel DNA fluorescent base analogue 3-hydroxychromone (3HC) to evaluate its suitability as a fluorescent reporter probe of structural transitions during protein-DNA interactions and its comparison with the current commercially available 2-aminopurine (aPu),...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Alexandra A., Kuznetsov, Nikita A., Vorobjev, Yuri N., Barthes, Nicolas P. F., Michel, Benoît Y., Burger, Alain, Fedorova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055743/
https://www.ncbi.nlm.nih.gov/pubmed/24925085
http://dx.doi.org/10.1371/journal.pone.0100007