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Axonal Localization of Ca(2+)-Dependent Activator Protein for Secretion 2 Is Critical for Subcellular Locality of Brain-Derived Neurotrophic Factor and Neurotrophin-3 Release Affecting Proper Development of Postnatal Mouse Cerebellum

Ca(2+)-dependent activator protein for secretion 2 (CAPS2) is a protein that is essential for enhanced release of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from cerebellar granule cells. We previously identified dex3, a rare alternative splice variant of CAPS2, which is over...

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Detalles Bibliográficos
Autores principales: Sadakata, Tetsushi, Kakegawa, Wataru, Shinoda, Yo, Hosono, Mayu, Katoh-Semba, Ritsuko, Sekine, Yukiko, Sato, Yumi, Saruta, Chihiro, Ishizaki, Yasuki, Yuzaki, Michisuke, Kojima, Masami, Furuichi, Teiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055771/
https://www.ncbi.nlm.nih.gov/pubmed/24923991
http://dx.doi.org/10.1371/journal.pone.0099524