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Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation

Leptin, a peripheral signal synthetized by the adipocyte to regulate energy metabolism, can also be produced by placenta, where it may work as an autocrine hormone. We have previously demonstrated that leptin promotes proliferation and survival of trophoblastic cells. In the present work, we aimed t...

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Detalles Bibliográficos
Autores principales: Toro, Ayelén Rayen, Maymó, Julieta Lorena, Ibarbalz, Federico Matías, Pérez, Antonio Pérez, Maskin, Bernardo, Faletti, Alicia Graciela, Margalet, Víctor Sánchez, Varone, Cecilia Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055782/
https://www.ncbi.nlm.nih.gov/pubmed/24922063
http://dx.doi.org/10.1371/journal.pone.0099187