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Leptin Is an Anti-Apoptotic Effector in Placental Cells Involving p53 Downregulation
Leptin, a peripheral signal synthetized by the adipocyte to regulate energy metabolism, can also be produced by placenta, where it may work as an autocrine hormone. We have previously demonstrated that leptin promotes proliferation and survival of trophoblastic cells. In the present work, we aimed t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055782/ https://www.ncbi.nlm.nih.gov/pubmed/24922063 http://dx.doi.org/10.1371/journal.pone.0099187 |