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Visualization and Communication of Pharmacometric Models With Berkeley Madonna
Population or other pharmacometric models are a useful means to describe, succinctly, the relationships between drug administration, exposure (concentration), and downstream changes in pharmacodynamic (PD) biomarkers and clinical endpoints, including the mixed effects of patient factors and random i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055786/ https://www.ncbi.nlm.nih.gov/pubmed/24872204 http://dx.doi.org/10.1038/psp.2014.13 |