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Visualization and Communication of Pharmacometric Models With Berkeley Madonna

Population or other pharmacometric models are a useful means to describe, succinctly, the relationships between drug administration, exposure (concentration), and downstream changes in pharmacodynamic (PD) biomarkers and clinical endpoints, including the mixed effects of patient factors and random i...

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Detalles Bibliográficos
Autores principales: Krause, A, Lowe, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055786/
https://www.ncbi.nlm.nih.gov/pubmed/24872204
http://dx.doi.org/10.1038/psp.2014.13