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An Invertebrate Warburg Effect: A Shrimp Virus Achieves Successful Replication by Altering the Host Metabolome via the PI3K-Akt-mTOR Pathway

In this study, we used a systems biology approach to investigate changes in the proteome and metabolome of shrimp hemocytes infected by the invertebrate virus WSSV (white spot syndrome virus) at the viral genome replication stage (12 hpi) and the late stage (24 hpi). At 12 hpi, but not at 24 hpi, th...

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Detalles Bibliográficos
Autores principales: Su, Mei-An, Huang, Yun-Tzu, Chen, I-Tung, Lee, Der-Yen, Hsieh, Yun-Chieh, Li, Chun-Yuan, Ng, Tze Hann, Liang, Suh-Yuen, Lin, Shu-Yu, Huang, Shiao-Wei, Chiang, Yi-An, Yu, Hon-Tsen, Khoo, Kay-Hooi, Chang, Geen-Dong, Lo, Chu-Fang, Wang, Han-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055789/
https://www.ncbi.nlm.nih.gov/pubmed/24945378
http://dx.doi.org/10.1371/journal.ppat.1004196