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Tug-of-war of microtubule filaments at the boundary of a kinesin- and dynein-patterned surface

Intracellular cargo is transported by multiple motor proteins. Because of the force balance of motors with mixed polarities, cargo moves bidirectionally to achieve biological functions. Here, we propose a microtubule gliding assay for a tug-of-war study of kinesin and dynein. A boundary of the two m...

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Detalles Bibliográficos
Autores principales: Ikuta, Junya, Kamisetty, Nagendra K., Shintaku, Hirofumi, Kotera, Hidetoshi, Kon, Takahide, Yokokawa, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055898/
https://www.ncbi.nlm.nih.gov/pubmed/24923426
http://dx.doi.org/10.1038/srep05281