A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans

Mitochondria are semi-autonomous organelles regulated by a complex network of proteins that are vital for many cellular functions. Because mitochondrial modulators can impact many aspects of cellular homeostasis, their identification and validation has proven challenging. It requires the measurement...

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Detalles Bibliográficos
Autores principales: Andreux, Pénélope A., Mouchiroud, Laurent, Wang, Xu, Jovaisaite, Virginija, Mottis, Adrienne, Bichet, Sabrina, Moullan, Norman, Houtkooper, Riekelt H., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055904/
https://www.ncbi.nlm.nih.gov/pubmed/24923838
http://dx.doi.org/10.1038/srep05285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055904/
https://www.ncbi.nlm.nih.gov/pubmed/24923838
http://dx.doi.org/10.1038/srep05285

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