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Microcephaly genes evolved adaptively throughout the evolution of eutherian mammals

BACKGROUND: Genes associated with the neurodevelopmental disorder microcephaly display a strong signature of adaptive evolution in primates. Comparative data suggest a link between selection on some of these loci and the evolution of primate brain size. Whether or not either positive selection or th...

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Detalles Bibliográficos
Autores principales: Montgomery, Stephen H, Mundy, Nicholas I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055943/
https://www.ncbi.nlm.nih.gov/pubmed/24898820
http://dx.doi.org/10.1186/1471-2148-14-120