Septic serum induces glucocorticoid resistance and modifies the expression of glucocorticoid isoforms receptors: a prospective cohort study and in vitro experimental assay

BACKGROUND: A protective role for glucocorticoid therapy in animal models of sepsis was shown many decades ago. In human sepsis, there is new interest in glucocorticoid therapy at a physiological dose after reports of improved response to vasopressor drugs and decreased mortality in a selected group...

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Detalles Bibliográficos
Autores principales: Guerrero, Julia, Gatica, Héctor A, Rodríguez, Margarita, Estay, Roberto, Goecke, Irmgadt Annelise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056039/
https://www.ncbi.nlm.nih.gov/pubmed/23759144
http://dx.doi.org/10.1186/cc12774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056039/
https://www.ncbi.nlm.nih.gov/pubmed/23759144
http://dx.doi.org/10.1186/cc12774

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