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Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

Background: There is increasing interest in investigating genetic risk models in empirical studies, but such studies are premature when the expected predictive ability of the risk model is low. We assessed how accurately the predictive ability of genetic risk models can be estimated in simulated dat...

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Detalles Bibliográficos
Autores principales: Kundu, Suman, Mihaescu, Raluca, Meijer, Catherina M. C., Bakker, Rachel, Janssens, A. Cecile J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056181/
https://www.ncbi.nlm.nih.gov/pubmed/24982668
http://dx.doi.org/10.3389/fgene.2014.00179