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Role of calcium desensitization in the treatment of myocardial dysfunction after deep hypothermic circulatory arrest

INTRODUCTION: Rewarming from deep hypothermic circulatory arrest (DHCA) produces calcium desensitization by troponin I (cTnI) phosphorylation which results in myocardial dysfunction. This study investigated the acute overall hemodynamic and metabolic effects of epinephrine and levosimendan, a calciu...

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Detalles Bibliográficos
Autores principales: Rungatscher, Alessio, Hallström, Seth, Giacomazzi, Alice, Linardi, Daniele, Milani, Elisabetta, Tessari, Maddalena, Luciani, Giovanni Battista, Scarabelli, Tiziano M, Mazzucco, Alessandro, Faggian, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056352/
https://www.ncbi.nlm.nih.gov/pubmed/24138817
http://dx.doi.org/10.1186/cc13071