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Differential protein occupancy profiling of the mRNA transcriptome

BACKGROUND: RNA-binding proteins (RBPs) mediate mRNA biogenesis, translation and decay. We recently developed an approach to profile transcriptome-wide RBP contacts on polyadenylated transcripts by next-generation sequencing. A comparison of such profiles from different biological conditions has the...

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Detalles Bibliográficos
Autores principales: Schueler, Markus, Munschauer, Mathias, Gregersen, Lea Haarup, Finzel, Ana, Loewer, Alexander, Chen, Wei, Landthaler, Markus, Dieterich, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056462/
https://www.ncbi.nlm.nih.gov/pubmed/24417896
http://dx.doi.org/10.1186/gb-2014-15-1-r15