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Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
BACKGROUND: Osteogenesis is a highly regulated developmental process and continues during the turnover and repair of mature bone. Runx2, the master regulator of osteoblastogenesis, directs a transcriptional program essential for bone formation through genetic and epigenetic mechanisms. While individ...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056528/ https://www.ncbi.nlm.nih.gov/pubmed/24655370 http://dx.doi.org/10.1186/gb-2014-15-3-r52 |