Cargando…

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis

BACKGROUND: Osteogenesis is a highly regulated developmental process and continues during the turnover and repair of mature bone. Runx2, the master regulator of osteoblastogenesis, directs a transcriptional program essential for bone formation through genetic and epigenetic mechanisms. While individ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Hai, Whitfield, Troy W, Gordon, Jonathan A R, Dobson, Jason R, Tai, Phillip W L, van Wijnen, Andre J, Stein, Janet L, Stein, Gary S, Lian, Jane B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056528/ https://www.ncbi.nlm.nih.gov/pubmed/24655370 http://dx.doi.org/10.1186/gb-2014-15-3-r52

Ejemplares similares

Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation
por: Tai, Phillip W. L., et al.
Publicado: (2017)

The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter
por: Barutcu, A. Rasim, et al.
Publicado: (2014)

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells
por: Trombly, Daniel J, et al.
Publicado: (2015)

Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition
por: Hong, Deli, et al.
Publicado: (2017)

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice
por: Farina, Nicholas H., et al.
Publicado: (2016)

Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis
por: Marcellini, Sylvain, et al.
Publicado: (2010)

The Role of RUNX2 in Osteosarcoma Oncogenesis
por: Martin, J. W., et al.
Publicado: (2011)

Runx2 Association with Progression of Prostate Cancer in Patients: Mechanisms Mediating Bone Osteolysis and Osteoblastic Metastatic Lesions
por: Akech, Jacqueline, et al.
Publicado: (2009)

Lansoprazole Upregulates Polyubiquitination of the TNF Receptor-Associated Factor 6 and Facilitates Runx2-mediated Osteoblastogenesis
por: Mishima, Kenichi, et al.
Publicado: (2015)

Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling
por: VanOudenhove, Jennifer J., et al.
Publicado: (2016)

TIEG1/KLF10 Modulates Runx2 Expression and Activity in Osteoblasts
por: Hawse, John R., et al.
Publicado: (2011)

Collagen Peptide Upregulates Osteoblastogenesis from Bone Marrow Mesenchymal Stem Cells through MAPK- Runx2
por: Elango, Jeevithan, et al.
Publicado: (2019)

Remifentanil promotes osteoblastogenesis by upregulating Runx2/osterix expression in preosteoblastic C2C12 cells
por: Yoon, Ji-Young, et al.
Publicado: (2019)

hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3
por: Dobson, Jason R, et al.
Publicado: (2014)

Transcriptional Auto-Regulation of RUNX1 P1 Promoter
por: Martinez, Milka, et al.
Publicado: (2016)

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking
por: Rose, Joshua T., et al.
Publicado: (2020)

Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2
por: Galea, Gabriel L., et al.
Publicado: (2020)

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility
por: Leong, David T, et al.
Publicado: (2010)

Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells
por: Taipaleenmäki, Hanna, et al.
Publicado: (2016)

Hedgehog Activation Regulates Human Osteoblastogenesis
por: Onodera, Shoko, et al.
Publicado: (2020)

Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells
por: Tandon, Manish, et al.
Publicado: (2012)

Effect of Salicornia herbacea on Osteoblastogenesis and Adipogenesis in Vitro
por: Karadeniz, Fatih, et al.
Publicado: (2014)

Toxic Effects of Indoxyl Sulfate on Osteoclastogenesis and Osteoblastogenesis
por: Shyu, Jia-Fwu, et al.
Publicado: (2021)

Restoration of Regenerative Osteoblastogenesis in Aged Mice: Modulation of TNF
por: Wahl, Elizabeth C, et al.
Publicado: (2010)

Efficient in vitro delivery of Noggin siRNA enhances osteoblastogenesis
por: Ghadakzadeh, S., et al.
Publicado: (2017)

Oridonin Attenuates Thioacetamide-Induced Osteoclastogenesis Through MAPK/NF-κB Pathway and Thioacetamide-Inhibited Osteoblastogenesis Through BMP-2/RUNX2 Pathway
por: Jin, XiaoLi, et al.
Publicado: (2023)

Oncogenic epigenetic control
por: Stein, Gary S., et al.
Publicado: (2016)

Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance
por: Browne, G, et al.
Publicado: (2012)

LINC01638 Sustains Human Mesenchymal Stem Cell Self-Renewal and Competency for Osteogenic Cell Fate
por: Gordon, Jonathan, et al.
Publicado: (2023)

The Cell Origin and Role of Osteoclastogenesis and Osteoblastogenesis in Vascular Calcification
por: Jiang, Wenhong, et al.
Publicado: (2021)

Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis
por: Boyce, Brendan F., et al.
Publicado: (2023)

LINC01638 sustains human mesenchymal stem cell self-renewal and competency for osteogenic cell fate
por: Gordon, Jonathan A. R., et al.
Publicado: (2023)

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation
por: Wu, Qiong, et al.
Publicado: (2016)

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells
por: Zaidi, Sayyed K., et al.
Publicado: (2017)

LncMIR181A1HG is a novel chromatin-bound epigenetic suppressor of early stage osteogenic lineage commitment
por: Tye, Coralee E., et al.
Publicado: (2022)

Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes
por: Messier, Terri L., et al.
Publicado: (2016)

Mineral trioxide aggregate induces osteoblastogenesis via Atf6
por: Maeda, Toyonobu, et al.
Publicado: (2015)

The role of Ca(2+)/Calcineurin/NFAT signalling pathway in osteoblastogenesis
por: Ren, Ranyue, et al.
Publicado: (2021)

The connection between BRG1, CTCF and topoisomerases at TAD boundaries
por: Barutcu, A. Rasim, et al.
Publicado: (2017)

Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis
por: Scheideler, Marcel, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_2du9qnf7nnrs3fdg0vip4l2dha