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The physiological functions of iron regulatory proteins in iron homeostasis - an update

Iron regulatory proteins (IRPs) regulate the expression of genes involved in iron metabolism by binding to RNA stem-loop structures known as iron responsive elements (IREs) in target mRNAs. IRP binding inhibits the translation of mRNAs that contain an IRE in the 5′untranslated region of the transcri...

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Detalles Bibliográficos
Autores principales: Zhang, De-Liang, Ghosh, Manik C., Rouault, Tracey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056636/
https://www.ncbi.nlm.nih.gov/pubmed/24982634
http://dx.doi.org/10.3389/fphar.2014.00124