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Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction

INTRODUCTION: Diaphragm weakness induced by prolonged mechanical ventilation may contribute to difficult weaning from the ventilator. Hypercapnia is an accepted side effect of low tidal volume mechanical ventilation, but the effects of hypercapnia on respiratory muscle function are largely unknown....

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Detalles Bibliográficos
Autores principales: Schellekens, Willem-Jan M, van Hees, Hieronymus WH, Kox, Matthijs, Linkels, Marianne, Acuña, Gilberto L Andrade, Dekhuijzen, PN Richard, Scheffer, Gert Jan, van der Hoeven, Johannes G, Heunks, Leo MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056638/
https://www.ncbi.nlm.nih.gov/pubmed/24506836
http://dx.doi.org/10.1186/cc13719