Nucleosomal Histone Proteins of L. donovani: A Combination of Recombinant H2A, H2B, H3 and H4 Proteins Were Highly Immunogenic and Offered Optimum Prophylactic Efficacy against Leishmania Challenge in Hamsters

The present study includes cloning and expression of recombinant Leishmania donovani histone proteins (rLdH2B, rLdH3, rLdH2A and rLdH4), assessment of their immunogenicity in Leishmania infected cured patients/endemic contacts as well as in cured hamsters and finally evaluation of their prophylactic...

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Detalles Bibliográficos
Autores principales: Baharia, Rajendra K., Tandon, Rati, Sahasrabuddhe, Amogh A., Sundar, Shyam, Dube, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057088/
https://www.ncbi.nlm.nih.gov/pubmed/24926878
http://dx.doi.org/10.1371/journal.pone.0097911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057088/
https://www.ncbi.nlm.nih.gov/pubmed/24926878
http://dx.doi.org/10.1371/journal.pone.0097911

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