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B and T lymphocyte attenuator expression on CD4(+) T-cells associates with sepsis and subsequent infections in ICU patients

INTRODUCTION: Sepsis is a deadly inflammatory condition that often leads to an immune suppressed state; however, the events leading to this state remain poorly understood. B and T lymphocyte attenuator (BTLA) is an immune-regulatory receptor shown to effectively inhibit CD4+ T-cell function. Therefo...

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Detalles Bibliográficos
Autores principales: Shubin, Nicholas J, Monaghan, Sean F, Heffernan, Daithi S, Chung, Chun-Shiang, Ayala, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057112/
https://www.ncbi.nlm.nih.gov/pubmed/24289156
http://dx.doi.org/10.1186/cc13131