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The Expression of the Hepatocyte SLAMF3 (CD229) Receptor Enhances the Hepatitis C Virus Infection

Hepatitis C virus (HCV) is a leading cause of cirrhosis and liver cancer worldwide. We recently characterized for the first time the expression of Signaling Lymphocyte Activating Molecule 3 (SLAMF3) in human hepatocytes and here, we report that SLAMF3 interacts with the HCV viral protein E2 and is i...

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Detalles Bibliográficos
Autores principales: Cartier, Flora, Marcq, Ingrid, Douam, Florian, Ossart, Christèle, Regnier, Aline, Debuysscher, Véronique, Lavillette, Dimitri, Bouhlal, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057114/
https://www.ncbi.nlm.nih.gov/pubmed/24927415
http://dx.doi.org/10.1371/journal.pone.0099601