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Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity

INTRODUCTION: Sepsis is characterized by systemic immune activation and neutrophil-mediated endothelial barrier integrity compromise, contributing to end-organ dysfunction. Studies evaluating endothelial barrier dysfunction induced by neutrophils from septic patients are lacking, despite its clinica...

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Detalles Bibliográficos
Autores principales: Fox, Elizabeth D, Heffernan, Daithi S, Cioffi, William G, Reichner, Jonathan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057230/
https://www.ncbi.nlm.nih.gov/pubmed/24099563
http://dx.doi.org/10.1186/cc13049