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Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models

To date, plants have been the major source of anticancer drugs. Boldine is a natural alkaloid commonly found in the leaves and bark of Peumus boldus. In this study, we found that boldine potently inhibited the viability of the human invasive breast cancer cell lines, MDA-MB-231 (48-hour IC(50) 46.5±...

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Detalles Bibliográficos
Autores principales: Paydar, Mohammadjavad, Kamalidehghan, Behnam, Wong, Yi Li, Wong, Won Fen, Looi, Chung Yeng, Mustafa, Mohd Rais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057328/
https://www.ncbi.nlm.nih.gov/pubmed/24944509
http://dx.doi.org/10.2147/DDDT.S58178