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Perivascular Adipose Tissue Inhibits Endothelial Function of Rat Aortas via Caveolin-1

Perivascular adipose tissue (PVAT)-derived factors have been proposed to play an important role in the pathogenesis of atherosclerosis. Caveolin-1 (Cav-1), occupying the calcium/calmodulin binding site of endothelial NO synthase (eNOS) and then inhibiting nitric oxide (NO) production, is also involv...

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Detalles Bibliográficos
Autores principales: Lee, Michelle Hui-Hsin, Chen, Shiu-Jen, Tsao, Cheng-Ming, Wu, Chin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057398/
https://www.ncbi.nlm.nih.gov/pubmed/24926683
http://dx.doi.org/10.1371/journal.pone.0099947