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Expansion of the Preimmune Antibody Repertoire by Junctional Diversity in Bos taurus

Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative significance has not been comprehensively studied....

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Detalles Bibliográficos
Autores principales: Liljavirta, Jenni, Niku, Mikael, Pessa-Morikawa, Tiina, Ekman, Anna, Iivanainen, Antti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057420/
https://www.ncbi.nlm.nih.gov/pubmed/24926997
http://dx.doi.org/10.1371/journal.pone.0099808