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Expansion of the Preimmune Antibody Repertoire by Junctional Diversity in Bos taurus
Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative significance has not been comprehensively studied....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057420/ https://www.ncbi.nlm.nih.gov/pubmed/24926997 http://dx.doi.org/10.1371/journal.pone.0099808 |