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High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria

INTRODUCTION: The high incidence of multidrug-resistant (MDR) bacteria among patients admitted to ICUs has determined an increase of tigecycline (TGC) use for the treatment of severe infections. Many concerns have been raised about the efficacy of this molecule and increased dosages have been propos...

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Detalles Bibliográficos
Autores principales: De Pascale, Gennaro, Montini, Luca, Pennisi, Mariano Alberto, Bernini, Valentina, Maviglia, Riccardo, Bello, Giuseppe, Spanu, Teresa, Tumbarello, Mario, Antonelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057423/
https://www.ncbi.nlm.nih.gov/pubmed/24887101
http://dx.doi.org/10.1186/cc13858