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Protease-activated receptor-1: key player in the sepsis coagulation-inflammation crosstalk

Protease-activated receptors (PARs) belong to the family of G protein-coupled receptors. Among the four members, PAR1 plays a major role in orchestrating the interactions between coagulation and inflammation. PAR1 has opposing functions during sepsis, and PAR1 blockade or activation may be alternati...

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Detalles Bibliográficos
Autores principales: Asehnoune, Karim, Moine, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057503/
https://www.ncbi.nlm.nih.gov/pubmed/23448515
http://dx.doi.org/10.1186/cc12502