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Protease-activated receptor-1: key player in the sepsis coagulation-inflammation crosstalk
Protease-activated receptors (PARs) belong to the family of G protein-coupled receptors. Among the four members, PAR1 plays a major role in orchestrating the interactions between coagulation and inflammation. PAR1 has opposing functions during sepsis, and PAR1 blockade or activation may be alternati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057503/ https://www.ncbi.nlm.nih.gov/pubmed/23448515 http://dx.doi.org/10.1186/cc12502 |