Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

INTRODUCTION: Development of resistance to tamoxifen is an important clinical issue in the treatment of breast cancer. Tamoxifen resistance may be the result of acquisition of epigenetic regulation within breast cancer cells, such as DNA methylation, resulting in changed mRNA expression of genes piv...

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Detalles Bibliográficos
Autores principales: Lin, Xue, Li, Jian, Yin, Guangliang, Zhao, Qian, Elias, Daniel, Lykkesfeldt, Anne E, Stenvang, Jan, Brünner, Nils, Wang, Jun, Yang, Huanming, Bolund, Lars, Ditzel, Henrik J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057522/
https://www.ncbi.nlm.nih.gov/pubmed/24355041
http://dx.doi.org/10.1186/bcr3588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057522/
https://www.ncbi.nlm.nih.gov/pubmed/24355041
http://dx.doi.org/10.1186/bcr3588

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