Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals

BACKGROUND: Majority of mutations found to date in the BRCA1/BRCA2 genes in breast and/or ovarian cancer families are point mutations or small insertions and deletions scattered over the coding sequence and splice junctions. Such mutations and sequence variants of BRCA1 and BRCA2 genes were previous...

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Detalles Bibliográficos
Autores principales: De Silva, Sumadee, Tennekoon, Kamani Hemamala, Karunanayake, Eric Hamilton, Amarasinghe, Indrani, Angunawela, Preethika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057568/
https://www.ncbi.nlm.nih.gov/pubmed/24906410
http://dx.doi.org/10.1186/1756-0500-7-344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057568/
https://www.ncbi.nlm.nih.gov/pubmed/24906410
http://dx.doi.org/10.1186/1756-0500-7-344

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