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GAP-Seq: a method for identification of DNA palindromes

BACKGROUND: Closely spaced long inverted repeats, also known as DNA palindromes, can undergo intrastrand annealing to form DNA hairpins. The ability to form these hairpins results in genome instability, difficulties in maintaining clones in Escherichia coli and major problems for most DNA sequencing...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Volfovsky, Natalia, Rattray, Alison, Chen, Xiongfong, Tanaka, Hisashi, Strathern, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057610/
https://www.ncbi.nlm.nih.gov/pubmed/24885769
http://dx.doi.org/10.1186/1471-2164-15-394