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The Minor Structural Difference between the Antioxidants Quercetin and 4′O-Methylquercetin Has a Major Impact on Their Selective Thiol Toxicity

Antioxidants act as intermediates by picking up the high unselective reactivity of radicals and transferring it to other molecules. In this process the reactivity is reduced and becomes selective. This channeling of the reactivity can cause selective toxicity. The antioxidant quercetin is known to c...

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Detalles Bibliográficos
Autores principales: Lemmens, Kristien J. A., Vrolijk, Misha F., Bouwman, Freek G., van der Vijgh, Wim J. F., Bast, Aalt, Haenen, Guido R. M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057684/
https://www.ncbi.nlm.nih.gov/pubmed/24786288
http://dx.doi.org/10.3390/ijms15057475