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Homology Modeling Study of Bovine μ-Calpain Inhibitor-Binding Domains

The activated mammalian CAPN-structures, the CAPN/CAST complex in particular, have become an invaluable target model using the structure-based virtual screening of drug candidates from the discovery phase to development for over-activated CAPN linked to several diseases, such as post-ischemic injury...

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Detalles Bibliográficos
Autores principales: Chai, Han-Ha, Lim, Dajeong, Lee, Seung-Hwan, Chai, Hee-Yeoul, Jung, Eunkyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057710/
https://www.ncbi.nlm.nih.gov/pubmed/24806345
http://dx.doi.org/10.3390/ijms15057897