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CB2 Receptor Activation Inhibits Melanoma Cell Transmigration through the Blood-Brain Barrier

During parenchymal brain metastasis formation tumor cells need to migrate through cerebral endothelial cells, which form the morphological basis of the blood-brain barrier (BBB). The mechanisms of extravasation of tumor cells are highly uncharacterized, but in some aspects recapitulate the diapedesi...

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Detalles Bibliográficos
Autores principales: Haskó, János, Fazakas, Csilla, Molnár, Judit, Nyúl-Tóth, Ádám, Herman, Hildegard, Hermenean, Anca, Wilhelm, Imola, Persidsky, Yuri, Krizbai, István A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057719/
https://www.ncbi.nlm.nih.gov/pubmed/24815068
http://dx.doi.org/10.3390/ijms15058063