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Inhibition of Autophagy Potentiates Atorvastatin-Induced Apoptotic Cell Death in Human Bladder Cancer Cells in Vitro

Statins are cholesterol reduction agents that exhibit anti-cancer activity in several human cancers. Because autophagy is a crucial survival mechanism for cancer cells under stress conditions, cooperative inhibition of autophagy acts synergistically with other anti-cancer drugs. Thus, this study inv...

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Detalles Bibliográficos
Autores principales: Kang, Minyong, Jeong, Chang Wook, Ku, Ja Hyeon, Kwak, Cheol, Kim, Hyeon Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057722/
https://www.ncbi.nlm.nih.gov/pubmed/24815071
http://dx.doi.org/10.3390/ijms15058106