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Efficient pH Dependent Drug Delivery to Target Cancer Cells by Gold Nanoparticles Capped with Carboxymethyl Chitosan

Doxorubicin (DOX) was immobilized on gold nanoparticles (AuNPs) capped with carboxymethyl chitosan (CMC) for effective delivery to cancer cells. The carboxylic group of carboxymethyl chitosan interacts with the amino group of the doxorubicin (DOX) forming stable, non-covalent interactions on the sur...

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Detalles Bibliográficos
Autores principales: Madhusudhan, Alle, Reddy, Gangapuram Bhagavanth, Venkatesham, Maragoni, Veerabhadram, Guttena, Kumar, Dudde Anil, Natarajan, Sumathi, Yang, Ming-Yeh, Hu, Anren, Singh, Surya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057728/
https://www.ncbi.nlm.nih.gov/pubmed/24821542
http://dx.doi.org/10.3390/ijms15058216