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DEFLATE Compression Algorithm Corrects for Overestimation of Phylogenetic Diversity by Grantham Approach to Single-Nucleotide Polymorphism Classification

Improvements in speed and cost of genome sequencing are resulting in increasing numbers of novel non-synonymous single nucleotide polymorphisms (nsSNPs) in genes known to be associated with disease. The large number of nsSNPs makes laboratory-based classification infeasible and familial co-segregati...

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Detalles Bibliográficos
Autores principales: Schlosberg, Arran, Lam, Brian Y. H., Yeo, Giles S. H., Clifton-Bligh, Roderick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057744/
https://www.ncbi.nlm.nih.gov/pubmed/24828207
http://dx.doi.org/10.3390/ijms15058491