Molecular Recognition of Agonist and Antagonist for Peroxisome Proliferator-Activated Receptor-α Studied by Molecular Dynamics Simulations

Peroxisome proliferator activated receptor-α (PPAR-α) is a ligand-activated transcription factor which plays important roles in lipid and glucose metabolism. The aim of this work is to find residues which selectively recognize PPAR-α agonists and antagonists. To achieve this aim, PPAR-α/13M and PPAR...

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Detalles Bibliográficos
Autores principales: Liu, Mengyuan, Wang, Lushan, Zhao, Xian, Sun, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057756/
https://www.ncbi.nlm.nih.gov/pubmed/24837836
http://dx.doi.org/10.3390/ijms15058743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057756/
https://www.ncbi.nlm.nih.gov/pubmed/24837836
http://dx.doi.org/10.3390/ijms15058743

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