Biological Evaluation and 3D-QSAR Studies of Curcumin Analogues as Aldehyde Dehydrogenase 1 Inhibitors

Aldehyde dehydrogenase 1 (ALDH1) is reported as a biomarker for identifying some cancer stem cells, and down-regulation or inhibition of the enzyme can be effective in anti-drug resistance and a potent therapeutic for some tumours. In this paper, the inhibitory activity, mechanism mode, molecular do...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Du, Zhiyun, Zhang, Changyuan, Tang, Zhikai, He, Yan, Zhang, Qiuyan, Zhao, Jun, Zheng, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057759/
https://www.ncbi.nlm.nih.gov/pubmed/24840575
http://dx.doi.org/10.3390/ijms15058795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057759/
https://www.ncbi.nlm.nih.gov/pubmed/24840575
http://dx.doi.org/10.3390/ijms15058795

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