Synthesis, Preliminary Bioevaluation and Computational Analysis of Caffeic Acid Analogues

A series of caffeic acid amides were designed, synthesized and evaluated for anti-inflammatory activity. Most of them exhibited promising anti-inflammatory activity against nitric oxide (NO) generation in murine macrophage RAW264.7 cells. A 3D pharmacophore model was created based on the biological...

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Detalles Bibliográficos
Autores principales: Liu, Zhiqian, Fu, Jianjun, Shan, Lei, Sun, Qingyan, Zhang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057760/
https://www.ncbi.nlm.nih.gov/pubmed/24857914
http://dx.doi.org/10.3390/ijms15058808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057760/
https://www.ncbi.nlm.nih.gov/pubmed/24857914
http://dx.doi.org/10.3390/ijms15058808

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