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Transition from Cyclosporine-Induced Renal Dysfunction to Nephrotoxicity in an in Vivo Rat Model

Cyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, regardless of nephrotoxicity, which depends on the duration of drug exposure. The mechanisms and biomarkers underlying the transition from CsA-induced renal dysfunction to nephrotoxicity deserve bette...

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Detalles Bibliográficos
Autores principales: Sereno, José, Rodrigues-Santos, Paulo, Vala, Helena, Rocha-Pereira, Petronila, Alves, Rui, Fernandes, João, Santos-Silva, Alice, Carvalho, Eugénia, Teixeira, Frederico, Reis, Flávio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057770/
https://www.ncbi.nlm.nih.gov/pubmed/24853130
http://dx.doi.org/10.3390/ijms15058979