Cargando…

Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation

BACKGROUND: Although long-term estrogen (E2) exposure is associated with increased breast cancer (BC) risk, and E2 appears to sustain growth of BC cells that express functional estrogen receptors (ERs), its role in promoting BC stem cells (CSCs) remains unclear. Considering that Gli1, part of the So...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Ying, Wang, Yunshan, Fan, Cong, Gao, Peng, Wang, Xiuwen, Wei, Guangwei, Wei, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057898/
https://www.ncbi.nlm.nih.gov/pubmed/24889938
http://dx.doi.org/10.1186/1476-4598-13-137