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Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation
BACKGROUND: Although long-term estrogen (E2) exposure is associated with increased breast cancer (BC) risk, and E2 appears to sustain growth of BC cells that express functional estrogen receptors (ERs), its role in promoting BC stem cells (CSCs) remains unclear. Considering that Gli1, part of the So...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057898/ https://www.ncbi.nlm.nih.gov/pubmed/24889938 http://dx.doi.org/10.1186/1476-4598-13-137 |