Cargando…

Loss of Mpzl3 Function Causes Various Skin Abnormalities and Greatly Reduced Adipose Depots

The rough coat (rc) spontaneous mutation causes sebaceous gland hypertrophy, hair loss and extracutaneous abnormalities including growth retardation. The rc mice have a missense mutation in the predicted immunoglobulin protein Mpzl3. In this study, we generated Mpzl3 knockout mice to determine its f...

Descripción completa

Detalles Bibliográficos
Autores principales: Leiva, Angel G., Chen, Anne L., Devarajan, Priyadharshini, Chen, Zhibin, Damanpour, Shadi, Hall, Jessica A., Bianco, Antonio C., Li, Jie, Badiavas, Evangelos V., Zaias, Julia, Miteva, Mariya, Romanelli, Paolo, Nouri, Keyvan, Wikramanayake, Tongyu Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057944/
https://www.ncbi.nlm.nih.gov/pubmed/24531688
http://dx.doi.org/10.1038/jid.2014.94