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Loss of Mpzl3 Function Causes Various Skin Abnormalities and Greatly Reduced Adipose Depots
The rough coat (rc) spontaneous mutation causes sebaceous gland hypertrophy, hair loss and extracutaneous abnormalities including growth retardation. The rc mice have a missense mutation in the predicted immunoglobulin protein Mpzl3. In this study, we generated Mpzl3 knockout mice to determine its f...
Autores principales: | Leiva, Angel G., Chen, Anne L., Devarajan, Priyadharshini, Chen, Zhibin, Damanpour, Shadi, Hall, Jessica A., Bianco, Antonio C., Li, Jie, Badiavas, Evangelos V., Zaias, Julia, Miteva, Mariya, Romanelli, Paolo, Nouri, Keyvan, Wikramanayake, Tongyu Cao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057944/ https://www.ncbi.nlm.nih.gov/pubmed/24531688 http://dx.doi.org/10.1038/jid.2014.94 |
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