Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

To increase our understanding of psoriasis, we utilized RNA-seq to assay the transcriptomes of lesional psoriatic and normal skin. We sequenced polyadenylated RNA-derived cDNAs from 92 psoriatic and 82 normal punch biopsies, generating an average of ~38 million single-end 80-bp reads per sample. Com...

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Detalles Bibliográficos
Autores principales: Li, Bingshan, Tsoi, Lam C., Swindell, William R., Gudjonsson, Johann E., Tejasvi, Trilokraj, Johnston, Andrew, Ding, Jun, Stuart, Philip E., Xing, Xianying, Kochkodan, James J., Voorhees, John J., Kang, Hyun M., Nair, Rajan P., Abecasis, Goncalo R., Elder, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954/
https://www.ncbi.nlm.nih.gov/pubmed/24441097
http://dx.doi.org/10.1038/jid.2014.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057954/
https://www.ncbi.nlm.nih.gov/pubmed/24441097
http://dx.doi.org/10.1038/jid.2014.28

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